HPV18 E7

Accession: H001479

Uniprot: Q9QNP6

Protein: E7

Organism: Human papillomavirus type 18

Function

E7 protein is transforming protein. It binds to pRB/p107 and promotes its complete degradation.

Sequence&Mutation

         .         .         .         .         .         .
MHGPKATLQN VLHLEPQNE PVDLLCHEQ SDSEEENDE DGVNHQHLP RRAEPQRHT
         .         .         .         .                    
MLCMCCKCEA IELVVESSA DLRAFQQLF KTLSFVCPW ASQQ 

Epitope&Mutation

>H001479_E7
MHGPKATLQNIVLHLEPQNEIPVDLLCHEQLSDSEEENDEIDGVNHQHLPARRAEPQRHTMLCMCCKCEARIELVVESSADDLRAFQQLFLKTLSFVCPWCASQQ
····················IPVDLLCHEQLSDSEEENDEID(DQ*0302)······················································
·································SEEENDEIDGVNHQHLPARR(A*0201)············································