HPV53 E2

Accession: H001437
Uniprot: B2WUW8
Protein: E2
Organism: Human papillomavirus type 53

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
METLCQRLNA QEKILDCFE DSKAITDHI YWKAVRQEN IYYKARENN TKLGHQVVP
. . . . . .
CLQVCKAKAC AIEIQIALE LCKTEYNME WTLRDVCES WYTEPKQCF KQGQHIEVW
. . . . . .
FDGSKDNRAE VVWKWVYYC EDGWCKVPS VNYEGIYYI DGHKTYYTN KDEATKYGC
. . . . . .
KGTWEVHMGK SIYCPDSVS TFRSNVSSV TVNEYYSHK PTTSTPVGT EASSSLRPG
. . . . . .
KRPRTTEPDS DSTTQSTTT RESYAQCVA NTDNTNNNT KHLPGGASC NTEINSGHK
. . . . . .
TAPVVHIKGE NRLKCLRYR QKHKQLFVT SSTYHWTNA SAVNNSYIT VYTDETQRQ
. .
KFLDIVKIPP VSLVLGHMT VDM