HPV11 E2

Accession: H001380

Uniprot: G0UE50

Protein: E2

Organism: Human papillomavirus type 11

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

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MEAIAKRLDA QDQLLELYE NSIDIHKHI HWKCIRLES LLHKAKQMG SHIGLQVVP
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PLTVSETKGH AIEMQMHLE LAKTKYGVE WTLQDTSYE WLTPPKRCF KQGNTVEVK
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FDGCEDNVME VVWTHIYLQ NDSWVKVTS VDAKGIYYT GQFKTYYVN NKEAQKYGS
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TNHWEVCYGS VICSPASVS TVREVSIAE TTYTPAQTT PTVSACTTE GVSAPPRKR
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ARGPSTNNTL VANIRSVDS INNIVTDNY KHQRRNNCH AATPIVQLQ DSNCLKCFR
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YRLNDKYRHL ELASSTWHW SPEAPHKNA VTLTYSSEE RQQFLNSVK PPTIRHKVG
                                                            
FMSLHLL     

Epitope&Mutation

>H001380_E2
MEAIAKRLDACQDQLLELYEENSIDIHKHIMHWKCIRLESVLLHKAKQMGLSHIGLQVVPPLTVSETKGHNAIEMQMHLESLAKTKYGVEPWTLQDTSYEMWLTPPKRCFKKQGNTVEVKFDGCEDNVMEYVVWTHIYLQDNDSWVKVTSSVDAKGIYYTCGQFKTYYVNFNKEAQKYGSTNHWEVCYGSTVICSPASVSSTVREVSIAEPTTYTPAQTTAPTVSACTTEDGVSAPPRKRARGPSTNNTLCVANIRSVDSTINNIVTDNYNKHQRRNNCHSAATPIVQLQGDSNCLKCFRYRLNDKYRHLFELASSTWHWASPEAPHKNAIVTLTYSSEEQRQQFLNSVKIPPTIRHKVGFMSLHLL
····AKRLDACQDQLLE(DRB1*0301)···················································································································································································································································································································································
····························································································································································································································································································PIVQLQGDSNCLKCFR(DRB1*0102)························································
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