HPV59 E2

Accession: H001288

NC: ACL12337.1

Uniprot: B9UPE2

Protein: E2

Organism: Human papillomavirus type 59

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
MQTVMDTLSQ LSVLQDQIL HYENDSKDI EHINYWKLV MENVILFAA ENNIHTLNH
         .         .         .         .         .         .
QVVPTFLVSK KACEAIELQ ALESLAQTE KNEQWTMQE CQELWQTAP KCFKKQGIT
         .         .         .         .         .         .
VEVRFDCSKE TMHYTSWTF YYVNDVGQW KTTGKVDFW LYYKVEEEQ YYVKFIHDA
         .         .         .         .         .         .
KKYGATDKWE HYNGKVIDC DSMCSTSDE VSTSGSSEQ SYPSATPPE TYLGPQTSN
         .         .         .         .         .         .
RQTKTGKRPR CGHTQHPQS SVSVDHCDN VVRLHPGNN RRHIPCSNT PIIHLKGDK
         .         .         .         .         .         .
NGLKCLRYRL KVHWLFENI STWHWTGNR SAKTGILTL YTSETQRNE LDTVKIPNS
                                                            
VQIHVGYMSV

DETAIL

EPITOPE & MUTATION