HPV58 E5

Accession: H000926

Uniprot: B6ZB03

Protein: E5

Organism: Human papillomavirus type 58

Function

It obstructs the growth suppression mechanisms: e.g. EGF receptor; activates mitogenic signalling pathways via transcription factors: c-Jun and c-Fos (important in ubiquitin pathway degradation of p53 complex by E6). Also inactivates p21 protein (p53 indu

Sequence&Mutation

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MILPIFVVCF LFLCLCIFL PLVLSISIY WLLVLVLLL VSVGSALRI LCYLIFLYI
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PMMCINFHAQ LTQQD