HPV11 E2

Accession: H000517

NC: AFC88071.1

Uniprot: D7GMV3

Protein: E2

Organism: Human papillomavirus type 11

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .
MEAIAKRLDA QDQLLELYE NSIDIHKHI HWKCIRLES LLHKAKQMG SHIGLQVVP
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PLTVSETKGH AIEMQMHLE LAKTQYGVE WTLQDTSYE WLTPPKRCF KQGNTVEVK
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FDGCEDNVME VVWTHIYLQ NDSWVKVTS VDAKGIYYT GQFKTYYVN NKEAQKYGS
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TNHWEVCYGS VICSPASVS TVREVSIAE TTYTPAQTT PTVSACTTE GVSAPPRKR
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ARGPSTNNTL VANIRSVDS INNIVTDNY KHQRRNNCH AATPIVQLQ DSNCLKCFR
         .         .         .         .         .         .
YRLNDKYRHL ELASSTWHW SPEAPHKNA VTLTYSSEE RQQFLNSVK PPTIRHKVG
                                                            
FMSLHLL     

Epitope&Mutation

>H000517_E2
MEAIAKRLDACQDQLLELYEENSIDIHKHIMHWKCIRLESVLLHKAKQMGLSHIGLQVVPPLTVSETKGHNAIEMQMHLESLAKTQYGVEPWTLQDTSYEMWLTPPKRCFKKQGNTVEVKFDGCEDNVMEYVVWTHIYLQDNDSWVKVTSSVDAKGIYYTCGQFKTYYVNFNKEAQKYGSTNHWEVCYGSTVICSPASVSSTVREVSIAEPTTYTPAQTTAPTVSACTTEDGVSAPPRKRARGPSTNNTLCVANIRSVDSTINNIVTDNYNKHQRRNNCHSAATPIVQLQGDSNCLKCFRYRLNDKYRHLFELASSTWHWASPEAPHKNAIVTLTYSSEEQRQQFLNSVKIPPTIRHKVGFMSLHLL
····AKRLDACQDQLLE(DRB1*0301)···················································································································································································································································································································································
····························································································································································································································································································PIVQLQGDSNCLKCFR(DRB1*0102)························································
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