HPV16 E1

Accession: H000376

Uniprot: I7AJA1

Protein: E1

Organism: Human papillomavirus type 16

Function

ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein.

Sequence&Mutation

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MADPAGTNGE GTGCNGWFY EAVVEKKTG AISDDENEN SDTGEDLVD IVNDNDYLT
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QADTETAHAL TAQEAKQHR AVQVLKRKY GSPLSDISG VDNNISPRL AICIEKQSR
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AAKRRLFESE SGYGNTEVE QQMLQVEGR ETETPCSQY GGSGGGCSQ HETETPCSQ
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YSGGSGGGCS YSSGSGGEG SERHTICQT LTNILNVLK SNAKAAMLA FKELYGVSF
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SELVRPFKSN STCCDWCIA FGLTPSIAD IKTLLQQYC YLHIQSLAC WGMVVLLLV
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RYKCGKNRET EKLLSKLLC SPMCMMIEP KLRSTAAAL WYKTGISNI EVYGDTPEW
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IQRQTVLQHS NDCTFELSQ VQWAYDNDI DDSEIAYKY QLADTNSNA AFLKSNSQA
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KIVKDCATMC HYKRAEKKQ SMSQWIKYR DRVDDGGDW QIVMFLRYQ VEFMSFLTA
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LKRFLQGIPK NCILLYGAA TGKSLFGMS MKFLQGSVI FVNSKSHFW QPLADAKIG
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MLDDATVPCW YIDDNLRNA DGNLVSMDV HRPLVQLKC PLLITSNIN GTDSRWPYL
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HNRLVVFTFP EFPFDENGN VYELNDKNW SFFSRTWSR SLHEDEDKE DGDSLPTFK
                                                            
CVSGQNTNTL     

Epitope&Mutation

>H000376_E1
MADPAGTNGEEGTGCNGWFYVEAVVEKKTGDAISDDENENDSDTGEDLVDFIVNDNDYLTQADTETAHALFTAQEAKQHRDAVQVLKRKYLGSPLSDISGCVDNNISPRLKAICIEKQSRAAKRRLFESEDSGYGNTEVETQQMLQVEGRHETETPCSQYSGGSGGGCSQRHETETPCSQYSGGSGGGCSQYSSGSGGEGVSERHTICQTPLTNILNVLKTSNAKAAMLAKFKELYGVSFSELVRPFKSNKSTCCDWCIAAFGLTPSIADSIKTLLQQYCLYLHIQSLACSWGMVVLLLVRYKCGKNRETIEKLLSKLLCVSPMCMMIEPPKLRSTAAALYWYKTGISNISEVYGDTPEWIQRQTVLQHSFNDCTFELSQMVQWAYDNDIVDDSEIAYKYAQLADTNSNASAFLKSNSQAKIVKDCATMCRHYKRAEKKQMSMSQWIKYRCDRVDDGGDWKQIVMFLRYQGVEFMSFLTALKRFLQGIPKKNCILLYGAANTGKSLFGMSLMKFLQGSVICFVNSKSHFWLQPLADAKIGMLDDATVPCWNYIDDNLRNALDGNLVSMDVKHRPLVQLKCPPLLITSNINAGTDSRWPYLHNRLVVFTFPNEFPFDENGNPVYELNDKNWKSFFSRTWSRLSLHEDEDKENDGDSLPTFKCVSGQNTNTL
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