HPV16 E1

Accession: H000331

Uniprot: B1A8X4

Protein: E1

Organism: Human papillomavirus type 16

Function

ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein.

Sequence&Mutation

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MADPAGTNGE GTGCNGWFY EAVVEKKTG AISDDENEN SDTGEDLVD IVNDNDYLT
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QAETETAHAL TAQEAKQHR AVQVLKRKY GSPLSDISG VDNNISPRL AICIEKQSR
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AAKRRLFESE SGYGNTEVE QQMLQVEGR ETETPCSQY GGSGGGCSQ SSGSGGEGV
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SERHTICQTP TNILNVLKT NAKAAMLAK KELYGVSFS LVRPFKSNK TCCDWCIAA
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FGLTPSIADS KTLLQQYCL LHIQSLACS GMVVLLLVR KCGKNRETI KLLSKLLCV
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SPMCMMIEPP LRSTAAALY YKTGISNIS VYGDTPEWI RQTVLQHSF DCTFDLSQM
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VQWAYDNDIV DSEIAYKYA LADTNSNAS FLKSNSQAK VKDCATMCR YKRAEKKQM
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SMSQWIKYRC RVDDGGDWK IVMFLRYQG EFMSFLTAL RFLQGIPKK CILLYGAAN
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TGKSLFGMSL KFLQGSVIC VNSKSHFWL PLADAKIGM DDATVPCWN IDDNLRNAL
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DGNLVSMDVK RPLVQLKCP LLITSNINA TDSRWPYLH RLVVFTFPN FPFDENGNP
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VYELNDKNWK FFSRTWSRL LHEDEDKEN GDSLPTFKC SGQNTNTL 

Epitope&Mutation

>H000331_E1
MADPAGTNGEEGTGCNGWFYVEAVVEKKTGDAISDDENENDSDTGEDLVDFIVNDNDYLTQAETETAHALFTAQEAKQHRDAVQVLKRKYLGSPLSDISGCVDNNISPRLKAICIEKQSRAAKRRLFESEDSGYGNTEVETQQMLQVEGRHETETPCSQYSGGSGGGCSQYSSGSGGEGVSERHTICQTPLTNILNVLKTSNAKAAMLAKFKELYGVSFSELVRPFKSNKSTCCDWCIAAFGLTPSIADSIKTLLQQYCLYLHIQSLACSWGMVVLLLVRYKCGKNRETIEKLLSKLLCVSPMCMMIEPPKLRSTAAALYWYKTGISNISEVYGDTPEWIQRQTVLQHSFNDCTFDLSQMVQWAYDNDIVDDSEIAYKYAQLADTNSNASAFLKSNSQAKIVKDCATMCRHYKRAEKKQMSMSQWIKYRCDRVDDGGDWKQIVMFLRYQGVEFMSFLTALKRFLQGIPKKNCILLYGAANTGKSLFGMSLMKFLQGSVICFVNSKSHFWLQPLADAKIGMLDDATVPCWNYIDDNLRNALDGNLVSMDVKHRPLVQLKCPPLLITSNINAGTDSRWPYLHNRLVVFTFPNEFPFDENGNPVYELNDKNWKSFFSRTWSRLSLHEDEDKENDGDSLPTFKCVSGQNTNTL
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