HPV16 L1

Accession: H000262

Uniprot: Q71C66

Protein: L1

Organism: Human papillomavirus type 16

Function

Major capsid protein. It can form virus-like particles. It forms the pentameric assembly unit of the viral shell.

Sequence&Mutation

         .         .         .         .         .         .
MQVTFIYILV TCYENDVNV HIFFQMSLW PSEATVYLP VPVSKVVST EYVARTNIY
         .         .         .         .         .         .
YHAGTSRLLA GHPYFPIKK NNNKILVPK SGLQYRVFR HLPDPNKFG PDTSFYNPD
         .         .         .         .         .         .
TQRLVWACVG EVGRGQPLG GISGHPLLN LDDTENASA AANAGVDNR CISMDYKQT
         .         .         .         .         .         .
QLCLIGCKPP GEHWGKGSP TNVAVTPGD PPLELINTV QDGDMVDTG GAMDFTTLQ
         .         .         .         .         .         .
ANKSEVPLDI TSICKYPDY KMVSEPYGD LFFYLRREQ FVRHLFNRA AVGENVPDD
         .         .         .         .         .         .
LYIKGSGSTA LASSNYFPT SGSMVTSDA IFNKPYWLQ AQGHNNGIC GNQLFVTVV
         .         .         .         .         .         .
DTTRSTNMSL AAISTSETT KNTNFKEYL HGEEYDLQF FQLCKITLT DVMTYIHSM
         .         .         .         .         .         .
NSTILEDWNF LQPPPGGTL DTYRFVTSQ IACQKHTPP PKEDPLKKY FWEVNLKEK
         .         .         .         .         .          
FSADLDQFPL RKFLLQAGL AKPKFTLGK KATPTTSST TTAKRKKRK 

Epitope&Mutation

>H000262_L1
MQVTFIYILVITCYENDVNVYHIFFQMSLWLPSEATVYLPPVPVSKVVSTDEYVARTNIYYHAGTSRLLAVGHPYFPIKKPNNNKILVPKVSGLQYRVFRIHLPDPNKFGFPDTSFYNPDTQRLVWACVGVEVGRGQPLGVGISGHPLLNKLDDTENASAYAANAGVDNRECISMDYKQTQLCLIGCKPPIGEHWGKGSPCTNVAVTPGDCPPLELINTVIQDGDMVDTGFGAMDFTTLQANKSEVPLDICTSICKYPDYIKMVSEPYGDSLFFYLRREQMFVRHLFNRAGAVGENVPDDLYIKGSGSTANLASSNYFPTPSGSMVTSDAQIFNKPYWLQRAQGHNNGICWGNQLFVTVVDTTRSTNMSLCAAISTSETTYKNTNFKEYLRHGEEYDLQFIFQLCKITLTADVMTYIHSMNSTILEDWNFGLQPPPGGTLEDTYRFVTSQAIACQKHTPPAPKEDPLKKYTFWEVNLKEKFSADLDQFPLGRKFLLQAGLKAKPKFTLGKRKATPTTSSTSTTAKRKKRKL
·······································PPVPVSKVVSTDEYVARTNIYYHA(DRB1*04)···········································································································································································································································································································································································································································································
··························································································VSGLQYRVFRIHLPDP(DRB1*03)································································································································································································································································································································································································································
····························································································································································································································································································································································ICWGNQLFV(A*0201)······································································································································································
································································································································································································································································································································································································································IHSMNSTIL(B*3901)··································································································
····················································································································································································································································································································································································································································································KYTFWEVNL(A24)·················································
·····················································································································································································································································································································································································································································································YTFWEVNLK(A11)················································