HPV58 E7

Accession: H000244

Uniprot: Q8QHQ2

Protein: E7

Organism: Human papillomavirus type 58

Function

E7 protein is transforming protein. It binds to pRB/p107 and promotes its complete degradation.

Sequence&Mutation

         .         .         .         .         .         .
MRGNNPTLRE ILDLHPEPT LFCYEQLCD SDEDEIGLD PDGQAQPAT NYYIVTCCY
         .         .         .                              
TCGTTVRLCI STATEVRTL QLLMGTCTI CPSCAQQ  

Epitope&Mutation

>H000244_E7
MRGNNPTLREYILDLHPEPTDLFCYEQLCDSSDEDEIGLDGPDGQAQPATANYYIVTCCYTCGTTVRLCINSTATEVRTLQQLLMGTCTIVCPSCAQQ
···································································LCINSTATE(A11)·················
·········································································ATEVRTLQQ(A11)···········
·······················································································CTIVCPSCA(A11)