HPV18 E7

Accession: H000196

Uniprot: A9XFJ1

Protein: E7

Organism: Human papillomavirus type 18

Function

E7 protein is transforming protein. It binds to pRB/p107 and promotes its complete degradation.

Sequence&Mutation

         .         .         .         .         .         .
MYGPKATLQD VLHLEPQNE PVDLLCHEQ SDSEEENDE DGVNHQHLP RRAEPQRHT
         .         .         .         .                    
MLCMCCKCEA IELVVESSA DLRAFQQLF STLSFVCPW ASQQ 

Epitope&Mutation

>H000196_E7
MYGPKATLQDIVLHLEPQNEIPVDLLCHEQLSDSEEENDEIDGVNHQHLPARRAEPQRHTMLCMCCKCEARIELVVESSADDLRAFQQLFLSTLSFVCPWCASQQ
······TLQDIVLHL(A*0201)··················································································
····················IPVDLLCHEQLSDSEEENDEID(DQ*0302)······················································
·································SEEENDEIDGVNHQHLPARR(A*0201)············································
·····················································································FQQLFLSTL(A*0201)···
·······················································································QLFLSTLSFV(A2)····