HPV55 E6

Accession: H000173

NC: AAA79478.1

Uniprot: Q80934

Protein: E6

Organism: Human papillomavirus type 55

Function

It is an oncogenic protein which causes transformation of host cell by binding to p53 tumour suppressor protein. For binding, it requires E6-associated protein (E6-AP) which is involved in the ubiquitin ligase pathway. E6-AP binds ubiquitin to the p53 pro

Sequence&Mutation

         .         .         .         .         .         .
MESANASTAA SIDQLCKEC IPMHHLQIL VFCRKTLTT EVYSFAYKQ YVVFRGNFP
         .         .         .         .         .         .
FAACAICLEL GKVNQFRHF FAGYALTVE ETKQSILDV IRCYLCHKP CHVEKVRHI
         .         .                                        
LEKARFIKLQ TWKGRCFHC TSCMETILP