HPV11 L1

Accession: H000113

NC: M14119.1

Uniprot: P04012

Protein: L1

Organism: Human papillomavirus type 11

Function

Major capsid protein. It can form virus-like particles. It forms the pentameric assembly unit of the viral shell.

Mutation

Sequence&Mutation

         .         .         .         .         .         .　　　　　G:5830
atgtggcggcctagcgacagcacagtatatgtgcctcctcccaaccctgtatccaaggtt　　　　　C:60
 M  W  R  P  S  D  S  T  V  Y  V  P  P  P  N  P  V  S  K  V 　　　　　P:20


         .         .         .         .         .         .　　　　　G:5890
gttgccacggatgcgtatgttaaacgcaccaacatattttatcatgccagcagttctaga　　　　　C:60
 V  A  T  D  A  Y  V  K  R  T  N  I  F  Y  H  A  S  S  S  R 　　　　　P:20


         .         .         .         .         .         .　　　　　G:5950
ctccttgctgtgggacatccatattactctatcaaaaaagttaacaaaacagttgtacca　　　　　C:60
 L  L  A  V  G  H  P  Y  Y  S  I  K  K  V  N  K  T  V  V  P 　　　　　P:20


         .         .         .         .         .         .　　　　　G:6010
aaggtgtctggatatcaatatagagtgtttaaggtagtgttgccagatcctaacaagttt　　　　　C:60
 K  V  S  G  Y  Q  Y  R  V  F  K  V  V  L  P  D  P  N  K  F 　　　　　P:20


         .         .         .         .         .         .　　　　　G:6070
gcattacctgattcatccctgtttgaccccactacacagcgtttagtatgggcgtgcaca　　　　　C:60
 A  L  P  D  S  S  L  F  D  P  T  T  Q  R  L  V  W  A  C  T 　　　　　P:20


         .         .         .         .         .         .　　　　　G:6130
gggttggaggtaggcaggggtcaacctttaggcgttggtgttagtgggcatccattgcta　　　　　C:60
 G  L  E  V  G  R  G  Q  P  L  G  V  G  V  S  G  H  P  L  L 　　　　　P:20


         .         .         .         .         .         .　　　　　G:6190
aacaaatatgatgatgtagaaaatagtggtgggtatggtggtaatcctggtcaggataat　　　　　C:60
 N  K  Y  D  D  V  E  N  S  G  G  Y  G  G  N  P  G  Q  D  N 　　　　　P:20


         .         .         .         .         .         .　　　　　G:6250
agggttaatgtaggtatggattataaacaaacccagctatgtatggtgggctgtgctcca　　　　　C:60
 R  V  N  V  G  M  D  Y  K  Q  T  Q  L  C  M  V  G  C  A  P 　　　　　P:20


         .         .         .         .         .         .　　　　　G:6310
ccgttaggtgaacattggggtaagggtacacaatgttcaaatacctctgtacaaaatggt　　　　　C:60
 P  L  G  E  H  W  G  K  G  T  Q  C  S  N  T  S  V  Q  N  G 　　　　　P:20


         .         .         .         .         .         .　　　　　G:6370
gactgccccccgttggaacttattaccagtgttatacaggatggggacatggttgataca　　　　　C:60
 D  C  P  P  L  E  L  I  T  S  V  I  Q  D  G  D  M  V  D  T 　　　　　P:20


         .         .         .         .         .         .　　　　　G:6430
ggctttggtgctatgaattttgcagacttacaaaccaataaatcggatgttccccttgat　　　　　C:60
 G  F  G  A  M  N  F  A  D  L  Q  T  N  K  S  D  V  P  L  D 　　　　　P:20


         .         .         .         .         .         .　　　　　G:6490
atttgtggaactgtctgcaaatatcctgattatttgcaaatggctgcagacccttatggt　　　　　C:60
 I  C  G  T  V  C  K  Y  P  D  Y  L  Q  M  A  A  D  P  Y  G 　　　　　P:20


         .         .         .         .         .         .　　　　　G:6550
gataggttgtttttttatttgcgaaaggaacaaatgtttgctagacacttttttaatagg　　　　　C:60
 D  R  L  F  F  Y  L  R  K  E  Q  M  F  A  R  H  F  F  N  R 　　　　　P:20


         .         .         .         .         .         .　　　　　G:6610
gccggtactgtgggggaacctgtgcctgatgacctgttggtaaaagggggtaataacaga　　　　　C:60
 A  G  T  V  G  E  P  V  P  D  D  L  L  V  K  G  G  N  N  R 　　　　　P:20


         .         .         .         .         .         .　　　　　G:6670
tcatctgtagctagtagtatttatgtacatacacctagtggctcattggtgtcttcagag　　　　　C:60
 S  S  V  A  S  S  I  Y  V  H  T  P  S  G  S  L  V  S  S  E 　　　　　P:20


         .         .         .         .         .         .　　　　　G:6730
gctcaattatttaataaaccatattggcttcaaaaggctcagggacataacaatggtatt　　　　　C:60
 A  Q  L  F  N  K  P  Y  W  L  Q  K  A  Q  G  H  N  N  G  I 　　　　　P:20


         .         .         .         .         .         .　　　　　G:6790
tgctggggaaaccacttgtttgttactgtggtagataccacacgcagtacaaatatgaca　　　　　C:60
 C  W  G  N  H  L  F  V  T  V  V  D  T  T  R  S  T  N  M  T 　　　　　P:20


         .         .         .         .         .         .　　　　　G:6850
ctatgtgcatctgtgtctaaatctgctacatacactaattcagattataaggaatacatg　　　　　C:60
 L  C  A  S  V  S  K  S  A  T  Y  T  N  S  D  Y  K  E  Y  M 　　　　　P:20


         .         .         .         .         .         .　　　　　G:6910
cgccatgtggaggagtttgatttacagtttatttttcaattgtgtagcattacattatct　　　　　C:60
 R  H  V  E  E  F  D  L  Q  F  I  F  Q  L  C  S  I  T  L  S 　　　　　P:20


         .         .         .         .         .         .　　　　　G:6970
gcagaagtcatggcctatatacacacaatgaatccttctgttttggaggactggaacttt　　　　　C:60
 A  E  V  M  A  Y  I  H  T  M  N  P  S  V  L  E  D  W  N  F 　　　　　P:20


         .         .         .         .         .         .　　　　　G:7030
ggtttatcgcctccaccaaatggtacactggaggatacttatagatatgtacagtcacag　　　　　C:60
 G  L  S  P  P  P  N  G  T  L  E  D  T  Y  R  Y  V  Q  S  Q 　　　　　P:20


         .         .         .         .         .         .　　　　　G:7090
gccattacctgtcagaaacccacacctgaaaaagaaaaacaggatccctataaggatatg　　　　　C:60
 A  I  T  C  Q  K  P  T  P  E  K  E  K  Q  D  P  Y  K  D  M 　　　　　P:20


         .         .         .         .         .         .　　　　　G:7150
agtttttgggaggttaacttaaaagaaaagttttcaagtgaattagatcagtttcccctt　　　　　C:60
 S  F  W  E  V  N  L  K  E  K  F  S  S  E  L  D  Q  F  P  L 　　　　　P:20


         .         .         .         .         .         .　　　　　G:7210
ggacgtaagtttttattgcaaagtggatatcgaggacggacgtctgctcgtacaggtata　　　　　C:60
 G  R  K  F  L  L  Q  S  G  Y  R  G  R  T  S  A  R  T  G  I 　　　　　P:20


         .         .         .         .         .         .　　　　　G:7270
aagcgcccagctgtgtctaagccctctacagcccccaaacgaaaacgtaccaaaaccaaa　　　　　C:60
 K  R  P  A  V  S  K  P  S  T  A  P  K  R  K  R  T  K  T  K 　　　　　P:20


                                                            　　　　　G:7276
aagtaa                                                      　　　　　C:6
 K                                                          　　　　　P:1

Epitope&Mutation

>H000113_L1
MWRPSDSTVYVPPPNPVSKVVATDAYVKRTNIFYHASSSRLLAVGHPYYSIKKVNKTVVPKVSGYQYRVFKVVLPDPNKFALPDSSLFDPTTQRLVWACTGLEVGRGQPLGVGVSGHPLLNKYDDVENSGGYGGNPGQDNRVNVGMDYKQTQLCMVGCAPPLGEHWGKGTQCSNTSVQNGDCPPLELITSVIQDGDMVDTGFGAMNFADLQTNKSDVPLDICGTVCKYPDYLQMAADPYGDRLFFYLRKEQMFARHFFNRAGTVGEPVPDDLLVKGGNNRSSVASSIYVHTPSGSLVSSEAQLFNKPYWLQKAQGHNNGICWGNHLFVTVVDTTRSTNMTLCASVSKSATYTNSDYKEYMRHVEEFDLQFIFQLCSITLSAEVMAYIHTMNPSVLEDWNFGLSPPPNGTLEDTYRYVQSQAITCQKPTPEKEKQDPYKDMSFWEVNLKEKFSSELDQFPLGRKFLLQSGYRGRTSARTGIKRPAVSKPSTAPKRKRTKTKK
·····························TNIFYHASSSRLLAV(DRB1*0701)······························································································································································································································································································································································································································································
···································································RVFKVVLPDPNKFAL(DRB1*0401)························································································································································································································································································································································································································
·························································································································································································ELITSVIQDGDMVDT(DRB1*0701)··································································································································································································································································································
···········································································································································································································AMNFADLQTNKSDVP(DRB1*0401)················································································································································································································································································
············································································································································································································································DPYGDRLFFYLRKEQMFAR(DRB1*1302)···········································································································································································································································
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·····························································································································································································································································································SIYVHTPSGSLVSSE(DRB1*0401)······························································································································································································
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···································································································································································································································································································································································YKEYMRHVEEFDLQF(DQB1*02)··························································································································
···························································································································································································································································································································································································SAEVMAYIHTMNPSV(DRB1*0701)································································································
···························································································································································································································································································································································································································DTYRYVQSQAITCQK(DRB1*0101)································································
···························································································································································································································································································································································································································DTYRYVQSQAITCQK(DRB1*0701)································································