HPV11 E7

Accession: H000090
NC: M14119.1
Uniprot: P04020
Protein: E7
Organism: Human papillomavirus type 11

Function

E7 protein is transforming protein. It binds to pRB/p107 and promotes its complete degradation.

Mutation

530-600
601-700
701-800
801-826
Legend:same sensemissenseinsertiondeletion
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Sequence&Mutation

         .         .         .         .         .         .     G:589
atgcatggaagacttgttaccctaaaggatatagtactagacctgcagcctcctgaccct     C:60
M H G R L V T L K D I V L D L Q P P D P      P:20


. . . . . .     G:649
gtagggttacattgctatgagcaattagaagacagctcagaagatgaggtggacaaggtg     C:60
V G L H C Y E Q L E D S S E D E V D K V      P:20


. . . . . .     G:709
gacaaacaagacgcacaacctttaacacaacattaccaaatactgacctgttgctgtgga     C:60
D K Q D A Q P L T Q H Y Q I L T C C C G      P:20


. . . . . .     G:769
tgtgacagcaacgtccgactggttgtggagtgcacagacggagacatcagacaactacaa     C:60
C D S N V R L V V E C T D G D I R Q L Q      P:20


. . . . .      G:826
gaccttttgctgggcacactaaatattgtgtgtcccatctgcgcaccaaaaccataa      C:57
D L L L G T L N I V C P I C A P K P      P:18


Legend:gene mutationamino acid mutation

Epitope&Mutation

Legend:mutationepitope
>H000090_E7
MHGRLVTLKDIVLDLQPPDPVGLHCYEQLEDSSEDEVDKVDKQDAQPLTQHYQILTCCCGCDSNVRLVVECTDGDIRQLQDLLLGTLNIVCPICAPKP
···RLVTLKDIV(A2)··················································································
······TLKDIVLDL(A*0201)···········································································
··············LQPPDPVGL(A*0201)···································································
··············································PLTQHYQIL(A*0201)···································
················································································DLLLGTLNI(A*0201)·
·················································································LLLGTLNIV(A*0201)