HPV58 E5
Accession: H000067
Uniprot: P26552
Protein: E5
Organism: Human papillomavirus type 58
Function
It obstructs the growth suppression mechanisms: e.g. EGF receptor; activates mitogenic signalling pathways via transcription factors: c-Jun and c-Fos (important in ubiquitin pathway degradation of p53 complex by E6). Also inactivates p21 protein (p53 indu
Sequence&Mutation
. . . . . . G:3951
atgatattacctatttttgttgtttgttttatactgtttttatgcttgtgcatttttttg C:60
M I L P I F V V C F I L F L C L C I F L P:20
. . . . . . G:4011
cggccattggtgctatctatttctatatatgcttggttgctggtgttggtgttgctgctt C:60
R P L V L S I S I Y A W L L V L V L L L P:20
. . . . . . G:4071
tgggtgtctgtggggtcggctctacgaatttttttctgttacttaatatttttatatata C:60
W V S V G S A L R I F F C Y L I F L Y I P:20
. . . . . G:4122
ccaatgatgtgtattaattttcatgcacaatacttaacccaacaagactaa C:51
P M M C I N F H A Q Y L T Q Q D P:16