HPV42 E5

Accession: H000065

Uniprot: P27227

Protein: E5

Organism: Human papillomavirus type 42

Function

It obstructs the growth suppression mechanisms: e.g. EGF receptor; activates mitogenic signalling pathways via transcription factors: c-Jun and c-Fos (important in ubiquitin pathway degradation of p53 complex by E6). Also inactivates p21 protein (p53 indu

Sequence&Mutation

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TVIGLQYCDS TCGTTGQKL LLLFIVVGA VVCVWISLQ YPYPVWASC ASYLTLVLL
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SWLQVLTYFD FFLCLIILG PSVLLTLLI LAIQ