HPV39 E5

Accession: H000064

Uniprot: P24833

Protein: E5

Organism: Human papillomavirus type 39

Function

It obstructs the growth suppression mechanisms: e.g. EGF receptor; activates mitogenic signalling pathways via transcription factors: c-Jun and c-Fos (important in ubiquitin pathway degradation of p53 complex by E6). Also inactivates p21 protein (p53 indu

Sequence&Mutation

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MILLVFLVWF VCIYICCNV LLPSVHVCA VWIIVFVFI IRTTPLEVF VYLLFFVLP
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MWLLHRLAMD I