HPV16 E4

Accession: H000047

NC: NP_041329.1

Uniprot: P06922

Protein: E4

Organism: Human papillomavirus type 16

Function

It is responsible for recognition and binding of origin of replication. It exists in two forms such as full length (transcriptional transactivator) and truncated (transcriptional repressor). The ratio of these found in the heterotrimeric complex, formed b

Sequence&Mutation

         .         .         .         .         .         .　　　　　G:3391
tattatgtcctacatctgtgtttagcagcaacgaagtatcctctcctgaaattattaggc　　　　　C:60
 Y  Y  V  L  H  L  C  L  A  A  T  K  Y  P  L  L  K  L  L  G 　　　　　P:20


         .         .         .         .         .         .　　　　　G:3451
agcacttggccaaccaccccgccgcgacccataccaaagccgtcgccttgggcaccgaag　　　　　C:60
 S  T  W  P  T  T  P  P  R  P  I  P  K  P  S  P  W  A  P  K 　　　　　P:20


         .         .         .         .         .         .　　　　　G:3511
aaacacagacgactatccagcgaccaagatcagagccagacaccggaaacccctgccaca　　　　　C:60
 K  H  R  R  L  S  S  D  Q  D  Q  S  Q  T  P  E  T  P  A  T 　　　　　P:20


         .         .         .         .         .         .　　　　　G:3571
ccactaagttgttgcacagagactcagtggacagtgctccaatcctcactgcatttaaca　　　　　C:60
 P  L  S  C  C  T  E  T  Q  W  T  V  L  Q  S  S  L  H  L  T 　　　　　P:20


         .         .         .         .                    　　　　　G:3619
gctcacacaaaggacggattaactgtaatagtaacactacacccatag            　　　　　C:48
 A  H  T  K  D  G  L  T  V  I  V  T  L  H  P                　　　　　P:15

DETAIL

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